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15 pages, 4489 KiB  
Article
Influence of the Long-Term Application of Management Practices (Tillage, Cover Crop and Glyphosate) on Greenhouse Gas Emissions and Soil Physical Properties
by Modupe Olufemi Doyeni, Skaidre Suproniene, Agne Versuliene, Loreta Meskauskiene and Grazina Kadziene
Sustainability 2024, 16(7), 2859; https://doi.org/10.3390/su16072859 (registering DOI) - 29 Mar 2024
Abstract
Soil treatments have a significant influence on the agricultural and environmental productivity of agricultural practices. Arable lands are one of the sources of greenhouse gas emissions (GHG) that are influenced by the chemical and physical properties of the soil and are an essential [...] Read more.
Soil treatments have a significant influence on the agricultural and environmental productivity of agricultural practices. Arable lands are one of the sources of greenhouse gas emissions (GHG) that are influenced by the chemical and physical properties of the soil and are an essential contributor to climate change. We aim to evaluate the long-term management of agricultural practices, such as different tillage systems, cover crops, and glyphosate, on GHG emissions and soil physical properties. The field trial involved three tillage systems (conventional tillage (CT), reduced tillage (RT), and no-tillage (NT)), along with variations in cover cropping (with and without cover crops) and glyphosate application (with and without glyphosate). These treatments were implemented during the cultivation of oilseed rape in 2022 as part of a cropping sequence consisting of five crops: winter wheat; winter oilseed rape; spring wheat; spring barley; and field pea. Greenhouse gas emissions (carbon dioxide (CO2), methane (CH4), and nitrous oxide (N2O)) were directly measured using a closed static chamber system. Through the examination of these management techniques, the soil’s physical properties over the studied period were assessed for their impact on GHG fluxes. The findings of the study reveal that N2O emissions were relatively low during the first month of measurement, with significant differences (p < 0.05) observed in the interaction between cover crop and glyphosate treatments. Additionally, N2O emissions were notably elevated in the reduced (0.079 µg m−2 h−1) and conventional tillage (0.097 µg m−2 h−1) treatments at the second month of measurement. Regarding CH4, increased emissions were observed in the reduced tillage and cover crop treatments. CO2 emissions exhibited variability across all of the investigated treatments. Notably, GHG fluxes spiked at the second measurement, signifying the maximum uptake of nutrients by the main plants during the growth phase. Greenhouse gas emissions leveled off across all of the treatments following the harvest, marking the end of the cultivation period. The influence of the deployed techniques varied across the determined physical parameters of the soil. The incorporation of cover crops contributed to improved water content and, further, to electrical conductivity. Glyphosate use showed no direct impact on physical properties of the soil while the different tillage treatments had varying effects on the distribution of the physical properties of the soil with respect to the degree of disturbance or tillage-induced changes. Additionally, GHG emissions were strongly correlated with precipitation at one week and two weeks before sampling, except for CO2, which showed a weaker correlation at two weeks before GHG sampling. The findings indicate that reduced and conventional tillage methods might adversely affect greenhouse gas emissions and plant functionality, particularly concerning nutrient release and uptake, especially in temperate climate conditions. Full article
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15 pages, 808 KiB  
Review
Sex Differences in Cognitive Reflection: A Meta-Analysis
by Inmaculada Otero, Alexandra Martínez, Dámaris Cuadrado, Mario Lado, Silvia Moscoso and Jesús F. Salgado
J. Intell. 2024, 12(4), 39; https://doi.org/10.3390/jintelligence12040039 (registering DOI) - 29 Mar 2024
Abstract
The current study presents a meta-analytic review of the differences between men and women in cognitive reflection (CR). The study also explores whether the type of CR test (i.e., numerical tests and verbal tests) moderates the relationship between CR and sex. The results [...] Read more.
The current study presents a meta-analytic review of the differences between men and women in cognitive reflection (CR). The study also explores whether the type of CR test (i.e., numerical tests and verbal tests) moderates the relationship between CR and sex. The results showed that men score higher than women on CR, although the magnitude of these differences was small. We also found out that the type of CR test moderates the sex differences in CR, especially in the numerical tests. In addition, the results showed that the length of numerical tests (i.e., number of items) does not affect the differences between men and women in CR. Finally, the implications of these results are discussed, and future research is suggested. Full article
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14 pages, 6061 KiB  
Article
Precipitation Variations in the Central Qilian Mountains since the 7th Century and Regional Differences: Evidence from Tree-Ring Data
by Taibang Zhang, Yong Zhang, Xuemei Shao and Xiuqi Fang
Forests 2024, 15(4), 624; https://doi.org/10.3390/f15040624 (registering DOI) - 29 Mar 2024
Abstract
The Qilian Mountains, located in northwest China and serving as a crucial water recharge area, have exhibited significant regional differences in precipitation patterns in recent decades. However, the limited temporal coverage of instrumental data has hindered a deep understanding of hydroclimate variations and [...] Read more.
The Qilian Mountains, located in northwest China and serving as a crucial water recharge area, have exhibited significant regional differences in precipitation patterns in recent decades. However, the limited temporal coverage of instrumental data has hindered a deep understanding of hydroclimate variations and regional differences. Further investigation into their long-term spatial and temporal precipitation characteristics is urgently needed. In this study, a new tree-ring-width chronology spanning 1743 years was established in the central Qilian Mountains using Qilian juniper (Juniperus przewalskii Kom.) samples. Significant correlations were found between the tree-ring indices and precipitation during both the growing and pre-growing seasons. Based on these correlations, annual precipitation from August of the previous year to July of the current year was reconstructed. The reconstruction model successfully explains 34.5% of the variation in precipitation during the calibration period. The analysis of the reconstructed series reveals notable interannual to multi-decadal dry–wet variability during the period from 614 AD to 2016 AD. The mid- to late-15th century emerges as the longest-lasting dry period, while the last decade stands out as the wettest. Comparative analysis with other precipitation reconstructions in the eastern and western Qilian Mountains reveals that regional drought events tend to be more pronounced and enduring. Low-frequency fluctuations on decadal to century scales show distinct wet and dry periods in the 12th–18th centuries in both the eastern and western parts of the Qilian Mountains, with weaker fluctuations in subsequent centuries. However, the central part of the Qilian Mountains exhibits opposite trends, possibly due to the complex interactions of multiple circulation systems. Full article
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23 pages, 10577 KiB  
Article
Deformation and Strength of Unsaturated Loess—Hydraulic Coupling Effects under Loads
by Hao Chai, Xi’an Li, Biao Qin, Weiping Wang and Mani Axel
Water 2024, 16(7), 997; https://doi.org/10.3390/w16070997 (registering DOI) - 29 Mar 2024
Abstract
The volumetric change in unsaturated loess during loading causes serious damage to the foundation and structure, accompanied by changes in hydraulic conditions. Therefore, quantifying the change in the load effect of loess under hydraulic coupling is of great significance for revealing the mechanism [...] Read more.
The volumetric change in unsaturated loess during loading causes serious damage to the foundation and structure, accompanied by changes in hydraulic conditions. Therefore, quantifying the change in the load effect of loess under hydraulic coupling is of great significance for revealing the mechanism of hydraulic interaction. This study conducts isotropic compression and undrained shear tests on unsaturated compacted loess, simultaneously introducing the strength parameter η to enhance the Glasgow coupled model (GCM). The objective is to elucidate the hydraulic and mechanical coupling mechanism, where saturation increases under mechanical effects lead to strength degradation. The results show that saturation increases under mechanical effects improve the compressibility of the sample, and saturation has a direct impact on the stress–strain relationship. The increase in water content and confining pressure increases the trend of the critical state stress ratio M decreasing, and the strain softening trend increases. The compression of volume during shear tests increases the saturation, changes the hydraulic characteristics of loess, and affects the deformation and strength of loess. The modified GCM improves the applicability and prediction accuracy of unsaturated loess under the same initial state. The research results are of great significance for revealing the hydraulic and mechanical behavior of loess. Full article
(This article belongs to the Section Hydraulics and Hydrodynamics)
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13 pages, 1170 KiB  
Article
Parameterization of Biomechanical Variables through Inertial Measurement Units (IMUs) in Occasional Healthy Runners
by ?lvaro Pareja-Cano, José María Arjona, Brian Caulfield and Antonio Cuesta-Vargas
Sensors 2024, 24(7), 2191; https://doi.org/10.3390/s24072191 (registering DOI) - 29 Mar 2024
Abstract
Running is one of the most popular sports practiced today and biomechanical variables are fundamental to understanding it. The main objectives of this study are to describe kinetic, kinematic, and spatiotemporal variables measured using four inertial measurement units (IMUs) in runners during treadmill [...] Read more.
Running is one of the most popular sports practiced today and biomechanical variables are fundamental to understanding it. The main objectives of this study are to describe kinetic, kinematic, and spatiotemporal variables measured using four inertial measurement units (IMUs) in runners during treadmill running, investigate the relationships between these variables, and describe differences associated with different data sampling and averaging strategies. A total of 22 healthy recreational runners (M age = 28 ± 5.57 yrs) participated in treadmill measurements, running at their preferred speed (M = 10.1 ± 1.9 km/h) with a set-up of four IMUs placed on tibias and the lumbar area. Raw data was processed and analysed over selections spanning 30 s, 30 steps and 1 step. Very strong positive associations were obtained between the same family variables in all selections. The temporal variables were inversely associated with the step rate variable in the selection of 30 s and 30 steps of data. There were moderate associations between kinetic (forces) and kinematic (displacement) variables. There were no significant differences between the biomechanics variables in any selection. Our results suggest that a 4-IMU set-up, as presented in this study, is a viable approach for parameterization of the biomechanical variables in running, and also that there are no significant differences in the biomechanical variables studied independently, if we select data from 30 s, 30 steps or 1 step for processing and analysis. These results can assist in the methodological aspects of protocol design in future running research. Full article
(This article belongs to the Special Issue Movement Biomechanics Applications of Wearable Inertial Sensors)
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11 pages, 1189 KiB  
Article
Early Serum Markers for Immune Checkpoint Inhibitor Induced Hypophysitis in Melanoma Patients
by Fouad Mitri, Devayani Machiraju, Christina Naoum and Jessica C. Hassel
Cancers 2024, 16(7), 1340; https://doi.org/10.3390/cancers16071340 (registering DOI) - 29 Mar 2024
Abstract
Background: Immune checkpoint inhibitors (ICIs) have shown promising anti-tumor activities and are widely used for the treatment of advanced cancers. However, they may lead to immune-related adverse events (irAEs) and some of them, such as hypophysitis, can be life-threatening. Here, early diagnosis is [...] Read more.
Background: Immune checkpoint inhibitors (ICIs) have shown promising anti-tumor activities and are widely used for the treatment of advanced cancers. However, they may lead to immune-related adverse events (irAEs) and some of them, such as hypophysitis, can be life-threatening. Here, early diagnosis is critical. Methods: We retrospectively analyzed 40 melanoma patients who developed hypophysitis during ICI treatment with either ipilimumab and/or anti-PD1 therapy and compared them to 40 control patients who did not develop hypophysitis during the ICI treatment, matched for age, gender, type of immunotherapy, and stage. Clinical data and blood values such as LDH, CRP, TSH, T3, T4, and absolute immune cell counts were retrieved from the medical records. Patient characteristics, laboratory values, progression-free survival, and overall survival were compared between the two groups. Results: Patients with ir-hypophysitis had a median age of 59 years, and most of them were male. Clinically, frequent symptoms were fatigue, headache, dizziness, and gastrointestinal symptoms such as nausea or abdominal pain. The onset of ir-hypophysitis differed much between ipilimumab- (median 8 weeks) and anti-PD1 (median 40 weeks)-induced hypophysitis (p < 0.001). At baseline, besides a slightly increased CRP level (p = 0.06), no differences were observed in patients who later developed hypophysitis compared to the control. After treatment started, hypophysitis patients showed a constant and significant decline in T4 levels from the start of therapy until diagnosis (p < 0.05), independent of the ICI treatment regime. However, a decline in T3 and TSH was only noted in patients with ipilimumab-induced ir-hypophysitis. Furthermore, serum sodium levels declined rapidly at the diagnosis of hypophysitis (p < 0.001). In addition, there was a constant increase in the absolute counts of eosinophils and lymphocytes from baseline in hypophysitis patients (p < 0.05). Conclusion: Ir-hypophysitis reveals different clinical pictures and onset times depending on the ICI regime used. Whereas a drop in T4 levels was indicative of developing hypophysitis independent of the ICI regime, TSH levels only declined in patients under ipilimumab-based ICI regimes. To best monitor our patients, it is important to recognize these differences. Full article
(This article belongs to the Special Issue Oncology: State-of-the-Art Research in Germany)
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19 pages, 15994 KiB  
Article
Geochemical Factors as a Tool for Distinguishing Geogenic from Anthropogenic Sources of Potentially Toxic Elements in the Soil
by Tomislav Brenko, Stanko Ru?i?i?, Niko Radoni?, Martina Puljko and Marko Cvetkovi?
Land 2024, 13(4), 434; https://doi.org/10.3390/land13040434 (registering DOI) - 29 Mar 2024
Abstract
Potentially toxic element (PTE) contamination of soils and their sources remains one of key global environmental concerns. Agricultural soil in Kalinovac, Podravina region, Croatia is the subject of this study. The main aims include determining the concentration and distribution of PTEs in the [...] Read more.
Potentially toxic element (PTE) contamination of soils and their sources remains one of key global environmental concerns. Agricultural soil in Kalinovac, Podravina region, Croatia is the subject of this study. The main aims include determining the concentration and distribution of PTEs in the soil, differentiation between possible geogenic and anthropogenic sources, and determining the correlation between the analysed PTEs and soil parameters. To achieve these objectives, geochemical analyses of the soil in the study area were carried out. Spatial distribution of the individual PTE contents, enrichment factors (EF), contamination factors (CF), and geoaccumulation index (Igeo) were created using GIS tools. In addition, statistical data processing was carried out, including the calculation of the correlation matrix, hierarchical cluster analysis (HCA), and factor analysis. The obtained results show that certain elements such as lead, chromium, copper, and cadmium were predominantly of anthropogenic origin in the study area, while others tended to have more geogenic origin. By applying different methods used in this study, it is possible to distinguish between geogenic and anthropogenic sources of PTEs in soils of this type. Full article
(This article belongs to the Section Soil-Sediment-Water Systems)
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15 pages, 6049 KiB  
Article
Analysis of the Impact of Hydraulic Gates on a Stabilized Tidal Inlet Structure: Mathematical Model and Data Measurements
by Alfonso Arrieta-Pastrana, Oscar E. Coronado-Hernández and Vicente S. Fuertes-Miquel
Hydrology 2024, 11(4), 46; https://doi.org/10.3390/hydrology11040046 (registering DOI) - 29 Mar 2024
Abstract
Tidal inlet structures are engineering projects with associated benefits related to flood control, water quality enhancement, and coastal protection. This study analyzes the performance of hydraulic gates on a stabilized inlet in estuarine systems by developing a simplified hydraulic model that considers inlet [...] Read more.
Tidal inlet structures are engineering projects with associated benefits related to flood control, water quality enhancement, and coastal protection. This study analyzes the performance of hydraulic gates on a stabilized inlet in estuarine systems by developing a simplified hydraulic model that considers inlet and outlet water levels. The proposed model was applied to the stabilized tidal inlet structure in Cartagena de Indias, Colombia. This model offers a practical tool for engineers and designers operating estuarine systems. The analysis focuses on the coastal lagoon of Ciénaga de la Virgen. The proposed model was successfully calibrated using two water sensors, with extreme input and outlet flow rates of approximately 260 m3/s and 110 m3/s, respectively. The average daily output volume in the system is 3,361,000 m3, while the average daily input volume is 3,200,000 m3. Consequently, the manipulation of the opening gates results in a decrease in the estuarine water level, potentially by as much as 25 cm, which local authorities can use to make decisions to reduce extreme water levels during flooding events. Full article
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17 pages, 10416 KiB  
Article
Approach and Management of Pregnancies with Risk Identified by Non-Invasive Prenatal Testing
by Miruna Gug, Adrian Ra?iu, Nicoleta Andreescu, Simona Farca?, Sorina Laitin and Cristina Gug
J. Pers. Med. 2024, 14(4), 366; https://doi.org/10.3390/jpm14040366 (registering DOI) - 29 Mar 2024
Abstract
This study represents our second investigation into NIPT, involving a more extensive patient cohort with a specific emphasis on the high-risk group. The high-risk group was subsequently divided into two further groups to compare confirmed cases versus unconfirmed via direct methods. The methodology [...] Read more.
This study represents our second investigation into NIPT, involving a more extensive patient cohort with a specific emphasis on the high-risk group. The high-risk group was subsequently divided into two further groups to compare confirmed cases versus unconfirmed via direct methods. The methodology encompassed the analysis of 1400 consecutive cases from a single genetic center in western Romania, where NIPT was used to assess the risk of specific fetal chromosomal abnormalities. All high-risk cases underwent validation through direct analysis of fetal cells obtained via invasive methods, including chorionic villus sampling and amniocentesis. The confirmation process utilized QF-PCR, karyotyping, and SNP-Array methods customized to each case. Results: A high risk of aneuploidy at NIPT was identified in 36 out of 1400 (2.57%) cases and confirmed in 28 cases. The study also detected an increased risk for copy number variations (CNVs) in 1% of cases, confirmed in two instances involving one large microdeletion and one large microduplication. Trisomy 21 was the exclusive anomaly where NIPT confirmed all cases with identified risk. High-risk NIPT results which were not validated by invasive methods, were classified as false positives; parents in these cases determined to continue the pregnancy. In conclusion, NIPT can serve as a screening method for all pregnancies; however, in high-risk cases, an invasive confirmation test is strongly recommended. Full article
(This article belongs to the Special Issue Personalized Approaches to Prenatal Screening and Diagnosis)
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12 pages, 1158 KiB  
Article
Utilization of Ocrelizumab within Different Treatment Strategies for Multiple Sclerosis: A 5-Year Population-Based Study
by Marcello Moccia, Giuseppina Affinito, Giuseppina Marrazzo, Tiziana Ciarambino, Paolo Di Procolo, Licia Confalonieri, Antonio Carotenuto, Maria Petracca, Roberta Lanzillo, Maria Triassi, Vincenzo Brescia Morra and Raffaele Palladino
Neurol. Int. 2024, 16(2), 394-405; https://doi.org/10.3390/neurolint16020029 (registering DOI) - 29 Mar 2024
Abstract
Background: We aim to provide up-to-date real-world evidence on the persistence, adherence, healthcare resource utilization, and costs of multiple sclerosis (MS) by comparing ocrelizumab to other disease-modifying treatments (DMTs) and within different DMT sequences. Methods: We included 3371 people with MS who first [...] Read more.
Background: We aim to provide up-to-date real-world evidence on the persistence, adherence, healthcare resource utilization, and costs of multiple sclerosis (MS) by comparing ocrelizumab to other disease-modifying treatments (DMTs) and within different DMT sequences. Methods: We included 3371 people with MS who first received or switched DMT prescriptions from January 2018 to December 2022; they were identified through hospital discharge records, drug prescriptions, and exemption codes from the Campania Region (South Italy). We calculated persistence (time from the first prescription to discontinuation or switching to another DMT), adherence (proportion of days covered (PDC)), DMT costs, and MS hospital admissions and related costs. Results: The most frequently prescribed DMT was dimethyl fumarate (n = 815; age 38.90 ± 11.91 years; 69.5% females), followed by ocrelizumab (n = 682; age 46.46 ± 11.29 years; 56.3%); 28.8% of the patients treated with ocrelizumab were naïve to DMTs. Using ocrelizumab as a statistical reference, the risk of discontinuation was higher for other highly active (HR = 6.32; 95%CI = 3.16, 12.63; p < 0.01) and low-/medium-efficacy DMTs (HR = 10.10; 95%CI = 5.10, 19.77; p < 0.01); adherence was lower for other highly active DMTs (Coeff = −0.07; 95%CI = −0.10, −0.04; p < 0.01) and low-/medium-efficacy DMTs (Coeff = −0.16; 95%CI = −0.19, −0.14; p < 0.01). monthly DMT costs were higher for other highly active DMTs (Coeff = 77.45; 95%CI = 29.36, 125.53; p < 0.01) but lower for low-/medium-efficacy DMTs (Coeff = −772.31; 95%CI = −816.95, −727.66; p < 0.01). The hospital admissions and related costs of MS were similar between ocrelizumab, other highly active DMTs, and other low-/medium-efficacy DMTs, and with ocrelizumab as the first-line DMT after other highly active DMTs and after low-/medium-efficacy DMTs, which was possibly due to the low number of observations. Conclusions: From 2018 to 2022, ocrelizumab was among the most frequently prescribed DMTs, with 28.8% prescriptions to incident MS patients, confirming its relevance in clinical practice. Ocrelizumab was associated with the highest persistence and adherence, pointing towards its favorable benefit–risk profile. The costs of ocrelizumab were lower than those of other highly active DMTs. Full article
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15 pages, 8960 KiB  
Article
A Signal-Processing-Based Simulation System for High-End Stereo Headsets
by Anna Zuccante, Alessandro Fiordelmondo, Pierluigi Bontempi and Sergio Canazza
Sensors 2024, 24(7), 2190; https://doi.org/10.3390/s24072190 (registering DOI) - 29 Mar 2024
Abstract
In recent years, headphones have become increasingly popular worldwide. There are numerous models on the market today, varying in technical characteristics and offering different listening experiences. This article presents an application for simulating the sound response of specific headphone models by physically wearing [...] Read more.
In recent years, headphones have become increasingly popular worldwide. There are numerous models on the market today, varying in technical characteristics and offering different listening experiences. This article presents an application for simulating the sound response of specific headphone models by physically wearing others. In the future, for example, this application could help to guide people who already own a pair of headphones during the decision-making process of purchasing a new headphone model. However, the potential fields of application are much broader. An in-depth study of digital signal processing was carried out with the implementation of a computational model. Prior to this, an analysis was performed on impulse response measurements of specific headphones, which allowed for a better understanding of the behavior of each set of headphones. Finally, an evaluation of the entire system was conducted through a listening test. The analysis of the results showed that the software works reasonably well in replicating the target headphones. We hope that this work will stimulate further efforts in the same direction. Full article
(This article belongs to the Special Issue Signal Processing and Machine Learning for Sensor Systems)
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19 pages, 4999 KiB  
Article
Energetic Features of H-Bonded and π-Stacked Assemblies in Pyrazole-Based Coordination Compounds of Mn(II) and Cu(II): Experimental and Theoretical Studies
by Mridul Boro, Trishnajyoti Baishya, Antonio Frontera, Miquel Barceló-Oliver and Manjit K. Bhattacharyya
Crystals 2024, 14(4), 318; https://doi.org/10.3390/cryst14040318 (registering DOI) - 29 Mar 2024
Abstract
Two new coordination compounds comprising Mn(II) and Cu(II) viz. [Mn(bz)2(Hdmpz)2(H2O)] (1) and [Cu(crot)2(Hdmpz)2] (2) (where, bz = benzoate; crot = crotonate; Hdmpz = 3, 5-dimethyl pyrazole) were synthesized and [...] Read more.
Two new coordination compounds comprising Mn(II) and Cu(II) viz. [Mn(bz)2(Hdmpz)2(H2O)] (1) and [Cu(crot)2(Hdmpz)2] (2) (where, bz = benzoate; crot = crotonate; Hdmpz = 3, 5-dimethyl pyrazole) were synthesized and characterized. The characterization involved a single crystal X-ray diffraction technique, FT-IR spectroscopy, electronic spectroscopy, TGA, and elemental analyses. Compounds 1 and 2 crystallize as mononuclear entities of Hdmpz with penta-coordinated Mn(II) and hexa-coordinated Cu(II), respectively. These complexes exhibit distorted trigonal bipyramidal and distorted octahedral geometries, respectively. A crystal structure analysis of compound 1 elucidates the existence of C–H⋯π and π-stacking interactions alongside O–H⋯O, N–H⋯O, and C–H⋯O H-bonding interactions contributing to the stabilization of the compound’s layered assembly. Similarly, in compound 2, the crystal structure stability is attributed to the presence of hydrogen bonding in conjugation with π-stacking interactions. We conducted theoretical investigations to analyze π⋯π, H-bonding, and antiparallel CH···π non-covalent interactions observed in compounds 1 and 2. DFT calculations were performed to find out the strength of these interactions energetically. Moreover, QTAIM and non-covalent interaction (NCI) plot index theoretical tools were employed to characterize them and evaluate the contribution of the H-bonds. Full article
(This article belongs to the Special Issue Coordination Complexes: Synthesis, Characterization and Application)
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20 pages, 22475 KiB  
Article
Assessing the Potential of Multi-Temporal Conditional Generative Adversarial Networks in SAR-to-Optical Image Translation for Early-Stage Crop Monitoring
by Geun-Ho Kwak and No-Wook Park
Remote Sens. 2024, 16(7), 1199; https://doi.org/10.3390/rs16071199 (registering DOI) - 29 Mar 2024
Abstract
The incomplete construction of optical image time series caused by cloud contamination is one of the major limitations facing the application of optical satellite images in crop monitoring. Thus, the construction of a complete optical image time series via image reconstruction of cloud-contaminated [...] Read more.
The incomplete construction of optical image time series caused by cloud contamination is one of the major limitations facing the application of optical satellite images in crop monitoring. Thus, the construction of a complete optical image time series via image reconstruction of cloud-contaminated regions is essential for thematic mapping in croplands. This study investigates the potential of multi-temporal conditional generative adversarial networks (MTcGANs) that use a single synthetic aperture radar (SAR) image acquired on a prediction date and a pair of SAR and optical images acquired on a reference date in the context of early-stage crop monitoring. MTcGAN has an advantage over conventional SAR-to-optical image translation methods as it allows input data of various compositions. As the prediction performance of MTcGAN depends on the input data composition, the variations in the prediction performance should be assessed for different input data combination cases. Such an assessment was performed through experiments using Sentinel-1 and -2 images acquired in the US Corn Belt. MTcGAN outperformed existing SAR-to-optical image translation methods, including Pix2Pix and supervised CycleGAN (S-CycleGAN), in cases representing various input compositions. In particular, MTcGAN was substantially superior when there was little change in crop vitality between the reference and prediction dates. For the SWIR1 band, the root mean square error of MTcGAN (0.021) for corn was significantly improved by 54.4% and 50.0% compared to Pix2Pix (0.046) and S-CycleGAN (0.042), respectively. Even when there were large changes in crop vitality, the prediction accuracy of MTcGAN was more than twice that of Pix2Pix and S-CycleGAN. Without considering the temporal intervals between input image acquisition dates, MTcGAN was found to be beneficial when crops were visually distinct in both SAR and optical images. These experimental results demonstrate the potential of MTcGAN in SAR-to-optical image translation for crop monitoring during the early growth stage and can serve as a guideline for selecting appropriate input images for MTcGAN. Full article
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12 pages, 7649 KiB  
Article
Experimental Investigation on Pressure and Flame Surface Oscillation in a Dual-Cavity Scramjet Combustor
by Wenhao Liao, Yidan Chen and Ningfei Wang
Energies 2024, 17(7), 1639; https://doi.org/10.3390/en17071639 (registering DOI) - 29 Mar 2024
Abstract
Pressure and flame surface oscillations are common in supersonic combustion instability. Understanding the characteristics, generation, maintenance, and interaction mechanisms of these oscillations is crucial. An experimental setup with an alcohol heater was used to study injection positions and fuel quantities in a dual-cavity [...] Read more.
Pressure and flame surface oscillations are common in supersonic combustion instability. Understanding the characteristics, generation, maintenance, and interaction mechanisms of these oscillations is crucial. An experimental setup with an alcohol heater was used to study injection positions and fuel quantities in a dual-cavity scramjet combustion chamber. High-frequency pressure sensors and high-speed equipment were employed in this research. The most significant pressure oscillation occurred at a global equivalence ratio of 1.2 with a frequency of 300 Hz and an amplitude of 43%. Mean oscillation was not affected by changes in equivalence ratio. Increased amplitude was linked to stronger flow instability, indicating that flow instability induced by unstable heat release plays a significant role in supersonic combustion instability. Full article
(This article belongs to the Section I2: Energy and Combustion Science)
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12 pages, 3391 KiB  
Article
Development of Loop-Mediated Isothermal Amplification (LAMP) Assays for the Rapid Detection of Toxigenic Aspergillus flavus and A. carbonarius in Nuts
by Wanissa Mellikeche, Alessandra Ricelli, Giulia Casini, Marilita Gallo, Nuray Baser, Giancarlo Colelli and Anna Maria D’Onghia
Int. J. Mol. Sci. 2024, 25(7), 3809; https://doi.org/10.3390/ijms25073809 (registering DOI) - 29 Mar 2024
Abstract
Aspergillus species create major postharvest problems due to the food losses caused by their mere presence and the hazardous mycotoxins they produce, such as aflatoxin B1 (AFB1) and ochratoxin A (OTA). These mycotoxins are mainly produced by A. flavus and A. carbonarius, [...] Read more.
Aspergillus species create major postharvest problems due to the food losses caused by their mere presence and the hazardous mycotoxins they produce, such as aflatoxin B1 (AFB1) and ochratoxin A (OTA). These mycotoxins are mainly produced by A. flavus and A. carbonarius, respectively. In this study, we developed a rapid detection method for the two aforementioned species based on loop-mediated isothermal amplification (LAMP). The primers were designed to target genes belonging to the mycotoxin clusters pks and aflT for A. carbonarius and A. flavus, respectively. Result visualization was carried out in real time via the detection of fluorescent signals. The method developed showed high sensitivity and specificity, with detection limits of 0.3 and 0.03 pg/reaction of purified DNA of A. carbonarius and A. flavus, respectively. The assays were further implemented on inoculated nuts, including pistachios and almonds, after one-step crude DNA extraction. These tests revealed a detection level of 0.5 spore/g that shows the effectiveness of LAMP as a rapid method for detecting potentially toxigenic Aspergillus spp. directly in food. The validation of the assays included tests on a larger scale that further confirmed their sensitivity and specificity, as well as enabling the production of ready-to-use LAMP prototype kits. These kits are easy to use and aim to simplify the screening of food samples in order to monitor the presence of specific Aspergillus contaminations. Full article
(This article belongs to the Special Issue Molecular Interactions between Plants and Pests)
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24 pages, 11999 KiB  
Article
Evaluation of Eco-Friendly Consolidating Treatments in Pugliese Tuff (Gravina Calcarenite) Used in Italian Heritage Buildings
by Jose Antonio Huesca-Tortosa, Yolanda Spairani-Berrio, Cristiano Giuseppe Coviello, Maria Francesca Sabbà, Fabio Rizzo and Dora Foti
Buildings 2024, 14(4), 940; https://doi.org/10.3390/buildings14040940 (registering DOI) - 29 Mar 2024
Abstract
This work evaluates the effectiveness of various consolidating treatments applied to Pugliese tuff (Gravina Calcarenite). This type of stone has been used in numerous historic buildings in the Puglia area (southeast of Italy), which presents durability problems due to high porosity, low cohesion [...] Read more.
This work evaluates the effectiveness of various consolidating treatments applied to Pugliese tuff (Gravina Calcarenite). This type of stone has been used in numerous historic buildings in the Puglia area (southeast of Italy), which presents durability problems due to high porosity, low cohesion between clasts, and low mechanical resistance. Eco-friendly treatments that generate CaCO3 have been selected, specifically bioconsolidant KBYO biological and lime water, which a priori are capable of consolidating without occluding the pores or reducing them excessively, thereby creating compounds similar to those contained in the stone and being respectful of the environment. Nano-sized treatments have also been tested, including nanosilica and nanolime, to compare results with eco-friendly treatments. The bioconsolidating treatment has been applied in two different ways, the usual way consisting of two applications a day for 7 days, as well as a double treatment that is applied in two batches of 7 days with a rest of 7 days between applications. Double treatment has shown a great improvement in consolidation compared to the usual 7-day application; this treatment has obtained the best results in both mechanical and petrophysical properties. This study not only demonstrates the effectiveness of the bioconsolidant but also expands eco-friendly conservation strategies to improve the preservation of historical structures built in calcarenite. Full article
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15 pages, 1857 KiB  
Article
An Escherichia coli-Based Phosphorylation System for Efficient Screening of Kinase Substrates
by Andrés Cayuela, Adela Villasante-Fernández, Antonio Corbalán-Acedo, Elena Baena-González, Alejandro Ferrando and Borja Belda-Palazón
Int. J. Mol. Sci. 2024, 25(7), 3813; https://doi.org/10.3390/ijms25073813 (registering DOI) - 29 Mar 2024
Abstract
Posttranslational modifications (PTMs), particularly phosphorylation, play a pivotal role in expanding the complexity of the proteome and regulating diverse cellular processes. In this study, we present an efficient Escherichia coli phosphorylation system designed to streamline the evaluation of potential substrates for Arabidopsis thaliana [...] Read more.
Posttranslational modifications (PTMs), particularly phosphorylation, play a pivotal role in expanding the complexity of the proteome and regulating diverse cellular processes. In this study, we present an efficient Escherichia coli phosphorylation system designed to streamline the evaluation of potential substrates for Arabidopsis thaliana plant kinases, although the technology is amenable to any. The methodology involves the use of IPTG-inducible vectors for co-expressing kinases and substrates, eliminating the need for radioactive isotopes and prior protein purification. We validated the system’s efficacy by assessing the phosphorylation of well-established substrates of the plant kinase SnRK1, including the rat ACETYL-COA CARBOXYLASE 1 (ACC1) and FYVE1/FREE1 proteins. The results demonstrated the specificity and reliability of the system in studying kinase-substrate interactions. Furthermore, we applied the system to investigate the phosphorylation cascade involving the A. thaliana MKK3-MPK2 kinase module. The activation of MPK2 by MKK3 was demonstrated to phosphorylate the Myelin Basic Protein (MBP), confirming the system’s ability to unravel sequential enzymatic steps in phosphorylation cascades. Overall, this E. coli phosphorylation system offers a rapid, cost-effective, and reliable approach for screening potential kinase substrates, presenting a valuable tool to complement the current portfolio of molecular techniques for advancing our understanding of kinase functions and their roles in cellular signaling pathways. Full article
(This article belongs to the Special Issue Regulation of Plant Protein Homeostasis under Stress)
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15 pages, 613 KiB  
Article
Nutritional and Phytochemical Characterization of Freeze-Dried Raspberry (Rubus idaeus): A Comprehensive Analysis
by Mirko Marino, Claudio Gardana, Marco Rendine, Dorothy Klimis-Zacas, Patrizia Riso, Marisa Porrini and Cristian Del Bo’
Foods 2024, 13(7), 1051; https://doi.org/10.3390/foods13071051 (registering DOI) - 29 Mar 2024
Abstract
Several studies have highlighted the beneficial effects of consuming red raspberries on human health thanks to their high content of phytochemicals. However, the products used in these studies, both in the raw or freeze-dried form, were not fully characterized for nutrient and phytochemical [...] Read more.
Several studies have highlighted the beneficial effects of consuming red raspberries on human health thanks to their high content of phytochemicals. However, the products used in these studies, both in the raw or freeze-dried form, were not fully characterized for nutrient and phytochemical composition. In this study, we aimed to determine the nutrient and non-nutrient compounds present in a freeze-dried red raspberry powder widely used by the food industry and consumers. The main sugars identified were fructose (12%), glucose (11%), and sucrose (11%). Twelve fatty acids were detected, with linoleic acid (46%), α-linolenic acid (20%), and oleic acid (15%) being the most abundant. Regarding micronutrients, vitamin C was the main hydro-soluble vitamin, while minerals, potassium, phosphorous, copper and magnesium were the most abundant, with concentrations ranging from 9 up to 96 mg/100 g, followed by manganese, iron and zinc, detected in the range 0.1–0.9 mg/100 g. Phytochemical analysis using UHPLC-DAD-HR-MS detection revealed the presence of Sanguiin H6 (0.4%), Lambertianin C (0.05%), and Sanguiin H-10 isomers (0.9%) as the main compounds. Among anthocyanins, the most representative compounds were cyanidin-3-sophoroside, cyanidin-3-glucoside and cyanidin-3-sambubioside. Our findings can serve as a reliable resource for the food industry, nutraceutical applications and for future investigations in the context of human health. Full article
(This article belongs to the Special Issue Plant-Based Food:From Nutritional Value to Health Benefits)
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27 pages, 13334 KiB  
Article
Influences of Climate Variability on Land Use and Land Cover Change in Rural South Africa
by Buster Percy Mogonong, Wayne Twine, Gregor Timothy Feig, Helga Van der Merwe and Jolene T. Fisher
Remote Sens. 2024, 16(7), 1200; https://doi.org/10.3390/rs16071200 (registering DOI) - 29 Mar 2024
Abstract
Changes in land use and land cover over space and time are an indication of biophysical, socio-economic, and political dynamics. In rural communities, land-based livelihood strategies such as agriculture are crucial for sustaining livelihoods in terms of food provision and as a source [...] Read more.
Changes in land use and land cover over space and time are an indication of biophysical, socio-economic, and political dynamics. In rural communities, land-based livelihood strategies such as agriculture are crucial for sustaining livelihoods in terms of food provision and as a source of local employment and income. In recent years, African studies have documented an overall decline in the extent of small-scale crop farming, with many crop fields left abandoned. This study uses rural areas in three former apartheid homelands in South Africa as a case study to quantify patterns and trends in the overall land cover change and small-scale agricultural lands related to changes in climate over a 38-year period. Random forest classification was applied on the Landsat imagery to detect land use and land cover change, achieving an overall accuracy of above 80%. Rainfall and temperature anomalies, as well as the Standardized Precipitation Evapotranspiration Index (SPEI) were used as climate proxies to assess the influence of climate variability on crop farming, as the systems investigated rely completely on rainfall. Agricultural land declined from 107.5 km2 to 49.5 km2 in Umhlabuyalingana; 54 km2 to 1.6 km2 in Joe Morolong; and 254.6 km2 to 7.4 km2 in Mangaung between 1984 and 2022. Declines in cropland cover, precipitation, and the SPEI were highly correlated. We argue that climatic variability influences crop farming activities; however, this could be one factor in a suite of drivers that interact together to influence the cropping practices in rural areas. Full article
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17 pages, 2630 KiB  
Article
Development and Characterization of a Hand Rub Gel Produced with Artisan Alcohol (Puntas), Silver Nanoparticles, and Saponins from Quinoa
by Oscar Analuiza, Belen Paredes, Alejandra Lascano, Santiago Bonilla and José-Luis Martínez-Guitarte
Gels 2024, 10(4), 234; https://doi.org/10.3390/gels10040234 (registering DOI) - 29 Mar 2024
Abstract
The emergence of the global pandemic (COVID-19) has directed global attention towards the importance of hygiene as the primary defense against various infections. In this sense, one of the frequent recommendations of the World Health Organization (WHO) is regular hand washing and the [...] Read more.
The emergence of the global pandemic (COVID-19) has directed global attention towards the importance of hygiene as the primary defense against various infections. In this sense, one of the frequent recommendations of the World Health Organization (WHO) is regular hand washing and the use of alcohol-based hand sanitizers. Ethanol is the most widely used alcohol due to its effectiveness in eliminating pathogens, ease of use, and widespread production. However, artisanal alcohol, generally used as a spirit drink, could be a viable alternative for developing sanitizing gels. In this study, the use of alcohol “Puntas”, silver nanoparticles, and saponins from quinoa was evaluated to produce hand sanitizer gels. The rheological, physicochemical, and antimicrobial properties were evaluated. In the previous assays, the formulations were adjusted to be similar in visual viscosity to the control gel. A clear decrease in the apparent viscosity was observed with increasing shear rate, and an inversely proportional relationship was observed with the amount of ethyl alcohol used in the formulations. The flow behavior index (n) values reflected a pseudoplastic behavior. Oscillatory dynamic tests were performed to analyze the viscoelastic behavior of gels. A decrease in storage modulus (G′) and an increase in loss modulus (G″) as a function of the angular velocity (ω) was observed. The evaluation of pH showed that the gels complied with the requirements to be in contact with the skin of the people, and the textural parameters showed that the control gel was the hardest. The use of artisan alcohol could be an excellent alternative to produce sanitizer gel and contribute to the requirements of the population. Full article
(This article belongs to the Special Issue Designing Gels for Antibacterial and Antiviral Agents)
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20 pages, 14188 KiB  
Article
Enhancing Coastal Risk Recognition: Assessing UAVs for Monitoring Accuracy and Implementation in a Digital Twin Framework
by Rui Yuan, Hezhenjia Zhang, Ruiyang Xu and Liyuan Zhang
Appl. Sci. 2024, 14(7), 2879; https://doi.org/10.3390/app14072879 (registering DOI) - 29 Mar 2024
Abstract
This paper addresses the intricate challenges of coastal management, particularly in rapidly forming tidal flats, emphasizing the need for innovative monitoring strategies. The dynamic coastal topography, exemplified by a newly formed tidal flat in Shanghai, underscores the urgency of advancements in coastal risk [...] Read more.
This paper addresses the intricate challenges of coastal management, particularly in rapidly forming tidal flats, emphasizing the need for innovative monitoring strategies. The dynamic coastal topography, exemplified by a newly formed tidal flat in Shanghai, underscores the urgency of advancements in coastal risk recognition. By utilizing a digital twin framework integrated with state-of-the-art unmanned aerial vehicles (UAVs), we systematically evaluate three configurations and identify the optimal setup incorporating real-time kinematics (RTK) and light detection and ranging (LiDAR). This UAV configuration excels in efficiently mapping the 3D coastal terrain. It has an error of less than 0.1 m when mapping mudflats at an altitude of 100 m. The integration of UAV data with a precise numerical ocean model forms the foundation of our dynamic risk assessment framework. The results showcase the transformative potential of the digital twin framework, providing unparalleled accuracy and efficiency in coastal risk recognition. Visualization through Unity Engine or Unreal Engine enhances accessibility, fostering community engagement and awareness. By predicting and simulating potential risks in real-time, this study offers a forward-thinking strategy for mitigating coastal dangers. This research not only contributes a comprehensive strategy for coastal risk management but also sets a precedent for the integration of cutting-edge technologies in safeguarding coastal ecosystems. The findings are significant in paving the way for a more resilient and sustainable approach to coastal management, addressing the evolving environmental pressures on our coastlines. Full article
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21 pages, 7623 KiB  
Article
Optimized Design for Vibration Reduction in a Residual Film Recovery Machine Frame Based on Modal Analysis
by Xinzhong Wang, Tianyu Hong, Weiquan Fang and Xingye Chen
Agriculture 2024, 14(4), 543; https://doi.org/10.3390/agriculture14040543 (registering DOI) - 29 Mar 2024
Abstract
The technology of plastic film mulching is widely applied in Xinjiang, but it also brings about serious issues of residual film pollution. Currently, the 1MSF-2.0 residual film recovery machine can effectively address the problem. However, it faces challenges such as high overall machine [...] Read more.
The technology of plastic film mulching is widely applied in Xinjiang, but it also brings about serious issues of residual film pollution. Currently, the 1MSF-2.0 residual film recovery machine can effectively address the problem. However, it faces challenges such as high overall machine weight and noticeable frame vibrations, which affect the stability of the entire machine operation. The frame, as the installation foundation, needs to bear loads and impact. Therefore, the reliability of the frame is crucial for the stability of the entire machine. Improving the frame’s vibration is of great importance. In response to the significant vibration issues during the operation of the 1MSF-2.0 residual film recovery machine, this paper utilized Workbench 2020 R2 to establish a finite element model of the machine frame and conducted static analysis to obtain strength information, thereby initially understanding the optimization space of the frame. Building upon this, Mechanical was employed to solve the first 14 natural frequencies and mode shapes of the frame, and the accuracy of the theoretical analysis was verified through modal testing. After analyzing the frequency characteristics of external excitation forces, it was found that the fourth-order natural frequency of the frame fell within the frequency range of the excitation force of the shaft of the straw grinder, causing resonance in the frame and necessitating structural optimization. The optimal results indicated that the optimized frame increased in mass by 4.41%, reduced the maximum stress value by 2.56 MPa, and increased the fourth-order natural frequency to 22.7 Hz, avoiding the frequency range of the excitation force of the shaft of the straw grinder, thus improving the resonance issue. This paper provides a reference for optimizing the design of the frame of the residual film recovery machine. Full article
(This article belongs to the Special Issue Design, Optimization and Analysis of Agricultural Machinery)
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25 pages, 1398 KiB  
Article
Comparison of Twenty Selected Fenugreek Genotypes Grown under Irrigated and Dryland Conditions: Morphology, Yield, Quality Properties and Antioxidant Activities
by Mahmut Camlica and Gulsum Yaldiz
Agronomy 2024, 14(4), 713; https://doi.org/10.3390/agronomy14040713 (registering DOI) - 29 Mar 2024
Abstract
In this study, 18 fenugreek genotypes and two cultivars were cultivated under irrigated and dryland conditions to determine the morphological, yield, quality, and bioactive properties. The morphological and seed yield values showed differences among the fenugreek genotypes and cultivars. The PI 286532 and [...] Read more.
In this study, 18 fenugreek genotypes and two cultivars were cultivated under irrigated and dryland conditions to determine the morphological, yield, quality, and bioactive properties. The morphological and seed yield values showed differences among the fenugreek genotypes and cultivars. The PI 286532 and PI 639185 genotypes for total alkaloid content and the PI 426973 and PI 572538 genotypes for trigonelline content were prominent under both irrigated and dryland conditions. The PI 215615 and PI 286532 genotypes were found to be rich in fixed oil contents under two growing conditions, while all fenugreek genotypes had high linoleic contents. The PI 568215 and PI 251640 genotypes and the gürarslan cultivar had the highest antioxidant activity compared with the other genotypes. The PI 215615 and PI 302448 genotypes and the gürarslan cultivar were found to be superior with respect to phenolic and flavonoid contents. Generally, the cluster analysis clustered the genotypes into two main groups and two sub-groups. Group B included more than 66% of the genotypes and cultivars. The biplot analysis accounted for over 53% of total variations. As a result of this study, most of the genotypes were found to be high in the examined properties, and these genotypes were good sources of natural components with potential applications in the food and pharmaceutical industries. Full article
(This article belongs to the Section Crop Breeding and Genetics)
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